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  Indian J Med Microbiol
 

Figure 1: The adverse events of topical diphenylcyclopropenone in treatment of alopecia areata. (a) Tense blisters developed on the scalp. (b and c) Hyperpigmentation manifested on the forehead, possibly due to dripping of diphenylcyclopropenone solution from the scalp, habitual wig-wearing, or hat-wearing. (d) Vitiligo developed from the site of diphenylcyclopropenone sensitization with an extension. (e and f) An alopecia universalis patient with near-total hair loss before (e) and after three months of diphenylcyclopropenone treatment (f). She achieved nearly full hair regrowth with new-onset vitiligo from the scalp to the nape after three months of diphenylcyclopropenone treatment.

Figure 1: The adverse events of topical diphenylcyclopropenone in treatment of alopecia areata. (a) Tense blisters developed on the scalp. (b and c) Hyperpigmentation manifested on the forehead, possibly due to dripping of diphenylcyclopropenone solution from the scalp, habitual wig-wearing, or hat-wearing. (d) Vitiligo developed from the site of diphenylcyclopropenone sensitization with an extension. (e and f) An alopecia universalis patient with near-total hair loss before (e) and after three months of diphenylcyclopropenone treatment (f). She achieved nearly full hair regrowth with new-onset vitiligo from the scalp to the nape after three months of diphenylcyclopropenone treatment.