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Figure 3: Diosmetin repressed inflammatory response of TNF-α-induced HaCaT. (a) Diosmetin, in a dosage dependent way, reduced mRNA expression of IL-6 and IL-8 in TNF-α-induced HaCaT.(b) Diosmetin, in a dosage dependent way, reduced protein expression of IL-6 and IL-8 in TNF-α-induced HaCaT. *P < 0.05, **P < 0.01, HaCaT: Human immortalized epidermal cells, TNF-α: tumor necrosis factor-alpha. |
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