Close
  Indian J Med Microbiol
 

Figure 2: Diosmetin repressed cell apoptosis of TNF-α-induced HaCaT, (a) Diosmetin, in a dosage dependent way, promoted the cell apoptosis of TNF-α-induced HaCaT using Annexin V-FITC Apoptosis Detection Kit. (b) Diosmetin, in a dosage dependent way, enhanced protein expression of Bax and reduced Bcl-2 in TNF-α-induced HaCaT. (c) Diosmetin, in a dosage dependent way, enhanced activities of caspase-3 and caspase-9 in TNF-α-induced HaCaT. *P < 0.05, **P < 0.01. HaCaT: Human immortalized epidermal cells, TNF-α: tumor necrosis factor-alpha, V-FITC: V-fluorescein isothiocyanate.

Figure 2: Diosmetin repressed cell apoptosis of TNF-α-induced HaCaT, (a) Diosmetin, in a dosage dependent way, promoted the cell apoptosis of TNF-α-induced HaCaT using Annexin V-FITC Apoptosis Detection Kit. (b) Diosmetin, in a dosage dependent way, enhanced protein expression of Bax and reduced Bcl-2 in TNF-α-induced HaCaT. (c) Diosmetin, in a dosage dependent way, enhanced activities of caspase-3 and caspase-9 in TNF-α-induced HaCaT. *<i>P</i> < 0.05, **<i>P</i> < 0.01. HaCaT: Human immortalized epidermal cells, TNF-α: tumor necrosis factor-alpha, V-FITC: V-fluorescein isothiocyanate.