Figure 2: Histopathological findings. (a) Diffuse lymphoid cell infiltration in the dermis (H and E, ×40). (b) The tumor cells were medium to large lymphoid cells (H and E, ×400). Immunohistochemically, the tumor cells showed diffuse and strong expression of (c) CD3, and (d) CD30 and were negative for (e) CD4 and (f) CD8 (× 200). (g) Fluorescent in situ hybridization analysis of the DUSP22-IRF4 gene (ZytoLight SPEC IRF4, DUSP22 Dual Color Break Apart Probe) demonstrated separate green and orange signals indicating rearrangement of DUSP22-IRF4 gene.