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  Indian J Med Microbiol
 

Figure 2: (a) Close-up view of the plaque shows a fine granular surface with uniform, tiny papules, many of which are surmounted by keratin spicules, better appreciated by the oblique view and (b) keratin spicules under dermatoscope ×10 (arrows). (c) Biopsy specimen of the left palm reveals multiple vertical columns of cornoid lamellae at the acrosyringia, which are enlarged with dilated lumens, (H and E, ×100). (d) Mutation analysis of GJB2 gene: (A) Proband, 263C>T, p.Ala88Val. (B) Parent, normal

Figure 2: (a) Close-up view of the plaque shows a fine granular surface with uniform, tiny papules, many of which are surmounted by keratin spicules, better appreciated by the oblique view and (b) keratin spicules under dermatoscope ×10 (arrows). (c) Biopsy specimen of the left palm reveals multiple vertical columns of cornoid lamellae at the acrosyringia, which are enlarged with dilated lumens, (H and E, ×100). (d) Mutation analysis of <i>GJB2</i> gene: (A) Proband, 263C>T, p.Ala88Val. (B) Parent, normal