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   2021| July-September  | Volume 39 | Issue 3  
    Online since September 20, 2021

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Eosinophilic pustular folliculitis associated with Demodex overgrowth or demodicosis on the face – A report of five cases
Hui-Peng Huang, Chao-Kai Hsu, Sheau-Chiou Chao, Chao-Chun Yang, Gwo-Shing Chen, Chih-Hung Lin, Chang-Ming Huang, Julia Yu-Yun Lee
July-September 2021, 39(3):132-136
Eosinophilic pustular folliculitis (EPF) is classified into Ofuji disease, immunosuppression-associated EPF, and infancy-associated EPF. The association of EPF with Demodex infestation is rarely reported. We report five cases of EPF with Demodex overgrowth. All patients were young females presenting with recurrent, itchy papulopustules on the face for 2 months to 2 years. Laboratory tests revealed eosinophilia (n = 2) and iron deficiency anemia (n = 1). Skin biopsy of papulopustular lesions was performed in each patient, and all revealed folliculocentric infiltration with eosinophils. Infundibular pustules containing Demodex mites were found in two patients. All patients had high Demodex densities examined by superficial needle-scraping method (7–18 mites/5 pustules) and/or thumbnail-squeezing method (37–255 mites/cm2). Based on the clinical and laboratory findings, the patients were either first treated as having demodicosis or as having EPF. According to the treatment responses, the cases might represent Demodex-induced EPF or EPF-like reaction (Cases 1–3) or demodicosis superimposed on EPF (Cases 4 and 5). In sum, we report five cases of EPF with Demodex overgrowth (demodicosis). These cases illustrate that the possibility of Demodex overgrowth should be considered in cases of EPF with incomplete treatment response to indomethacin and/or oral corticosteroids. Conversely, EPF should be considered in cases of demodicosis with incomplete responses to antiparasitic treatment.
  3,960 236 -
The influence of gender and smoking on hidradenitis suppurativa: A retrospective study of 161 patients in Taiwan
Chia-Bao Chu, Wan-Lin Li, Sheng-Hsiang Lin, Chao-Kai Hsu, Chao-Chun Yang, Shaw-Jenq Tsai
July-September 2021, 39(3):125-131
Background: Hidradenitis suppurativa (HS) is a severe dermatological disease that significantly reduces life quality. However, the etiology of this disease remains largely unknown. Objectives: We sought to identify the factors associated with clinical presentation and the severity of HS. The features of HS between genders and smokers/nonsmokers were compared. Methods: A single-center retrospective study of 161 patients with HS was conducted and analyzed. Results: The male-to-female ratio in HS was approximately 2:1 in Taiwan. The severity of HS was significantly associated with smoking (odds ratio 2.20, P = 0.018). HS in men more frequently occurred in the gluteal region. Nonsmokers in HS tended to have earlier onset age and axillary lesions. Smokers were prone to have exclusive gluteal involvement and negative family history of HS. Conclusion: Our data revealed smoking correlated with the severity of HS. Smoking status and gender influence the clinical characteristics in HS.
  3,162 203 2
Recent advances in noninvasive imaging of the skin – dermoscopy and optical coherence tomography
Li-Wen Chiu, Stephen Chu-Sung Hu
July-September 2021, 39(3):115-117
  2,785 235 1
Histoid leprosy complicated with Charcot neuroarthropathy: A case report
Jen-Hao Hsu, Yu-Hung Wu, Pa-Fan Hsiao
July-September 2021, 39(3):137-138
  2,558 224 -
Recalcitrant giant genital wart treated with the combination of measles–mumps–rubella vaccine and human papillomavirus vaccine
Tzu-Yu Weng, Woan-Ruoh Lee, Donald Liu
July-September 2021, 39(3):141-142
  2,553 138 -
Facilitated delivery of topical steroids after fractional ablative carbon dioxide laser failed to prevent the postthyroidectomy hypertrophic scar
Ko-Chien Lin, Shao-Chun Wu, Shun-Yu Chi, Hui-Ping Lin, Cen-Hung Lin, Yueh-Ju Tsai, Mu-Han Hsieh, Shiun-Yuan Hsu, Ching-Hua Hsieh
July-September 2021, 39(3):118-124
Background: The ablative fractional laser can destroy the epidermal barrier and enhance the infiltration and distribution of drugs into the dermis. Objectives: This study was designed to investigate whether steroid delivery followed by the fractional ablative laser can prevent the formation of postthyroidectomy scar. Methods: This prospective split-scar design study recruited 12 adult female patients who underwent thyroidectomy between March 2018 and December 2018. The whole scar was treated with a fractional ablative carbon dioxide laser with topical 0.05% clobetasol propionate ointment only applied on the treatment side. The Patient and Observer Scar Assessment Scale (POSAS) questionnaire was used for outcome assessment at 1 year following the first treatment. The follow-up assessment by scar esthetic scale using digital photographs at 6 months and 1 year after first treatment was also done by three blinded plastic surgeons. Results: The POSAS revealed the improvement was not significant on vascularity, pigmentation, thickness, relief, pliability, surface area, and overall opinion on the improvement (all P > 0.05). The digital photographs evaluation also did not reveal a significant difference between the treatment side and control side. The overall esthetic score in the assessment of digital photographs was 4.4 ± 1.5, 4.2 ± 1.9, and 3.4 ± 1.9 at 6 months, and 2.8 ± 1.9, 3.1 ± 1.9, and 2.4 ± 2.1 at 1 year, with 0–10 indicating totally identical to significantly different comparing the whole scar with surrounding normal skin. Conclusion: This prospective scar-split study revealed that the application of topical steroid after fractional ablative carbon dioxide laser has no significant effect to prevent the formation of postthyroidectomy scar.
  2,425 220 -
Yellow vesicular palmar eruption in a young man with hyperbilirubinemia: Eccrine chromhidrosis
Ya-Hui Hsieh
July-September 2021, 39(3):165-166
  2,408 111 -
Actinic granuloma successfully treated with low-dose doxycycline
Chun-Hsien Huang, Ching-Chi Chi, Wei-Ti Chen
July-September 2021, 39(3):149-150
  2,332 133 -
Actinomycetoma caused by Nocardia brasiliensis successfully treated with antibiotics: A case report
Yi-Teng Hung, Ting-Shu Wu, Yu-Han Hsueh, Hsuan-Ning Wang, Pei-Lun Sun
July-September 2021, 39(3):139-140
  2,004 181 -
Juvenile folliculotropic mycosis fungoides mimicking tinea capitis: A case report and literature review
Lai-Ying Lu, Hsi Yen, Pei-Lun Sun, Yen-Lin Huang, Chun-Wei Lu
July-September 2021, 39(3):145-146
  1,997 130 -
Complete remission of scleredema adultorum of Buschke associated with multiple myeloma after bortezomib-based treatment and autologous peripheral blood stem cell transplantation
Hsing-Jou Su, Yao-Yu Chang, Chau Yee Ng
July-September 2021, 39(3):155-156
  1,882 110 -
Treatment with sirolimus gel for folliculocystic and collagen hamartoma in tuberous sclerosis complex
Yuko Ehara, Yuichi Yoshida, Hiromi Higaki-Mori, Osamu Yamamoto
July-September 2021, 39(3):163-164
  1,771 119 1
Spontaneous regression of hidroacanthoma simplex after skin biopsy
Takahiro Koike, Hiraku Kokubu, Toshifumi Takahashi, Toshihiro Tanaka, Noriki Fujimoto
July-September 2021, 39(3):147-148
  1,735 114 -
Postirradiation multiple minute digitate porokeratosis: A case report
Xiao-Feng Yao, Yu-Hung Wu
July-September 2021, 39(3):143-144
  1,668 124 -
Statins did not reduce the mortality risk in patients with bullous pemphigoid: A population-based cohort study
Chen-Yi Wu, Chun-Ying Wu, Yi-Hsian Lin, Yun-Ting Chang
July-September 2021, 39(3):153-154
  1,633 100 2
Squamous cell carcinoma arising in a verrucous cyst-like lesion: A case report
Chi-Hsuan Chen, Chao-Chun Yang, Yu-Yun Lee, Yin-Yu Ho
July-September 2021, 39(3):151-152
  1,430 124 -
Development of cutaneous hyperpigmentation and vitiligo during the recovery period of palmoplantar pustulosis in a patient of synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome: A case report
Mingwei Ma, Yanying Yu, Yihan Cao, Chen Li
July-September 2021, 39(3):157-158
  1,142 114 -
Radiation-induced bullous pemphigoid in a patient with Kaposi's sarcoma
Jia-Di Lin, Sung-Jen Hung
July-September 2021, 39(3):159-160
  1,130 104 1
Pediatric generalized lichen nitidus successfully treated with narrow-band ultraviolet B phototherapy: A case report
Ya-Tang Yang, Yu Yu
July-September 2021, 39(3):161-162
  1,024 52 -