Dermatologica Sinica

BRIEF REPORT
Year
: 2021  |  Volume : 39  |  Issue : 4  |  Page : 202--205

Calcified angioleiomyoma – Histopathologic and ultrasonographic analysis of the calcification process


Ming-Hsiu Hsieh1, Miki Izumi2, Yukio Nakatani3, Kuniaki Ohara5 
1 Department of Environmental Immuno-Dermatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan; Department of Dermatology, Akasaka Toranomon Clinic, Minato Tokyo, Japan
2 Department of Medical Education, Showa University, Shinagawa, Tokyo, Japan
3 Department of Pathology, Yokosuka Kyosai Hospital, Kanagawa, Yokosuka, Japan

Correspondence Address:
Dr. Ming-Hsiu Hsieh
Department of Environmental Immuno-Dermatology, Yokohama City University Graduate School of Medicine, 3-9, Fukura, Yokohama Shi Kanazawa Ku, Kanagawa Ken, 236-0004
Japan

Historically, angioleiomyoma is a subtype of leiomyoma that comprises about 4%–5% of all benign soft tissue tumors, and calcifications occur in 2%–3% of them. Because of the very low incidence of calcifications, their mechanism of formation is still unknown. In this article, we present the five cases of angioleiomyomas with calcification and discuss the ultrasonographic features in three of those cases. In general, from the aspect of ultrasonography, angioleiomyomas are recognized as hypoechogenic homogenous structures with peritumoral or intratumoral vascularity. However, our cases revealed heterogeneity or hyperechogenicity in inclusions, which has never been reported before. Histologically, calcifications were found not only under the dystrophic pathway which were considered in the past literature but also have the possibility under the metastatic pathway. According to our findings, we also classified the ultrasonographic patterns into three patterns according to the progression and distribution of calcifications. This is the first report to identify the location and possible pathways of calcifications and to classify the ultrasonographic features of calcified angioleiomyomas.


How to cite this article:
Hsieh MH, Izumi M, Nakatani Y, Ohara K. Calcified angioleiomyoma – Histopathologic and ultrasonographic analysis of the calcification process.Dermatol Sin 2021;39:202-205


How to cite this URL:
Hsieh MH, Izumi M, Nakatani Y, Ohara K. Calcified angioleiomyoma – Histopathologic and ultrasonographic analysis of the calcification process. Dermatol Sin [serial online] 2021 [cited 2023 Jan 30 ];39:202-205
Available from: https://www.dermsinica.org/article.asp?issn=1027-8117;year=2021;volume=39;issue=4;spage=202;epage=205;aulast=Hsieh;type=0