Dermatologica Sinica

ORIGINAL ARTICLE
Year
: 2021  |  Volume : 39  |  Issue : 3  |  Page : 118--124

Facilitated delivery of topical steroids after fractional ablative carbon dioxide laser failed to prevent the postthyroidectomy hypertrophic scar


Ko-Chien Lin1, Shao-Chun Wu2, Shun-Yu Chi3, Hui-Ping Lin1, Cen-Hung Lin1, Yueh-Ju Tsai1, Mu-Han Hsieh1, Shiun-Yuan Hsu4, Ching-Hua Hsieh1 
1 Department of Plastic Surgery, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan
2 Department of Anesthesiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan
3 Department of General Surgery, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan
4 Department of Trauma Surgery, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan

Correspondence Address:
Prof. Ching-Hua Hsieh
No. 123, Ta-Pei Road, Niaosong District, Kaohsiung City 83301
Taiwan

Background: The ablative fractional laser can destroy the epidermal barrier and enhance the infiltration and distribution of drugs into the dermis. Objectives: This study was designed to investigate whether steroid delivery followed by the fractional ablative laser can prevent the formation of postthyroidectomy scar. Methods: This prospective split-scar design study recruited 12 adult female patients who underwent thyroidectomy between March 2018 and December 2018. The whole scar was treated with a fractional ablative carbon dioxide laser with topical 0.05% clobetasol propionate ointment only applied on the treatment side. The Patient and Observer Scar Assessment Scale (POSAS) questionnaire was used for outcome assessment at 1 year following the first treatment. The follow-up assessment by scar esthetic scale using digital photographs at 6 months and 1 year after first treatment was also done by three blinded plastic surgeons. Results: The POSAS revealed the improvement was not significant on vascularity, pigmentation, thickness, relief, pliability, surface area, and overall opinion on the improvement (all P > 0.05). The digital photographs evaluation also did not reveal a significant difference between the treatment side and control side. The overall esthetic score in the assessment of digital photographs was 4.4 ± 1.5, 4.2 ± 1.9, and 3.4 ± 1.9 at 6 months, and 2.8 ± 1.9, 3.1 ± 1.9, and 2.4 ± 2.1 at 1 year, with 0–10 indicating totally identical to significantly different comparing the whole scar with surrounding normal skin. Conclusion: This prospective scar-split study revealed that the application of topical steroid after fractional ablative carbon dioxide laser has no significant effect to prevent the formation of postthyroidectomy scar.


How to cite this article:
Lin KC, Wu SC, Chi SY, Lin HP, Lin CH, Tsai YJ, Hsieh MH, Hsu SY, Hsieh CH. Facilitated delivery of topical steroids after fractional ablative carbon dioxide laser failed to prevent the postthyroidectomy hypertrophic scar.Dermatol Sin 2021;39:118-124


How to cite this URL:
Lin KC, Wu SC, Chi SY, Lin HP, Lin CH, Tsai YJ, Hsieh MH, Hsu SY, Hsieh CH. Facilitated delivery of topical steroids after fractional ablative carbon dioxide laser failed to prevent the postthyroidectomy hypertrophic scar. Dermatol Sin [serial online] 2021 [cited 2021 Oct 25 ];39:118-124
Available from: https://www.dermsinica.org/article.asp?issn=1027-8117;year=2021;volume=39;issue=3;spage=118;epage=124;aulast=Lin;type=0