Dermatologica Sinica

CASE REPORT
Year
: 2019  |  Volume : 37  |  Issue : 4  |  Page : 226--228

IgG/IgA pemphigus presenting with mixed clinical features of pemphigus erythematosus and IgA pemphigus


Shih-Jyun Yang1, Hua-En Lee1, Chih-Hao Chang1, Chun-Bing Chen2 
1 Department of Dermatology, Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital, Linkou, Taipei and Keelung; College of Medicine, Chang Gung University, Taoyuan, Taiwan
2 Department of Dermatology, Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital, Linkou, Taipei and Keelung; College of Medicine, Chang Gung University, Taoyuan, Taiwan; Department of Dermatology, Xiamen Chang Gung Hospital, Xiamen; Whole-Genome Research Core Laboratory of Human Diseases, Chang Gung Memorial Hospital, Keelung; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan

Correspondence Address:
Dr. Chun-Bing Chen
Department of Dermatology, Chang Gung Memorial Hospital, Keelung Branch, No. 222, Maijin Road, Anle District, Keelung City

IgG/IgA pemphigus is a phenotype of atypical pemphigus with variable clinical, histological, and immunological manifestations. We describe a unique case of IgG/IgA pemphigus in a 58-year-old male presenting with mixed features of pemphigus erythematosus and IgA pemphigus. The diagnosis is made based on the histopathological examination and intercellular deposition of IgG and IgA throughout the epidermis on direct immunofluorescence test. The patient responded favorably to the combination therapy of dapsone and low-dose systemic steroids.


How to cite this article:
Yang SJ, Lee HE, Chang CH, Chen CB. IgG/IgA pemphigus presenting with mixed clinical features of pemphigus erythematosus and IgA pemphigus.Dermatol Sin 2019;37:226-228


How to cite this URL:
Yang SJ, Lee HE, Chang CH, Chen CB. IgG/IgA pemphigus presenting with mixed clinical features of pemphigus erythematosus and IgA pemphigus. Dermatol Sin [serial online] 2019 [cited 2022 Aug 18 ];37:226-228
Available from: https://www.dermsinica.org/article.asp?issn=1027-8117;year=2019;volume=37;issue=4;spage=226;epage=228;aulast=Yang;type=0