Dermatologica Sinica

CASE REPORT
Year
: 2019  |  Volume : 37  |  Issue : 3  |  Page : 166--169

A case of pretibial myxedema associated with hypothyroidism and thyroid-stimulating hormone receptor antibodies


Sang Yong Oh1, Han Kyoung Cho2, Yoon Yang Jung3, Min-Kyung Lee4 
1 Department of Internal Medicine, Myongji Hospital, Hanyang University College of Medicine, Gyeonggi-do, Republic of Korea
2 Department of Dermatology, Myongji Hospital, Hanyang University College of Medicine, Gyeonggi-do, Republic of Korea
3 Department of Pathology, Myongji Hospital, Hanyang University College of Medicine, Gyeonggi-do, Republic of Korea
4 Department of Internal Medicine, Division of Endocrinology and Metabolism, Myongji Hospital, Hanyang University College of Medicine, Gyeonggi-do, Republic of Korea

Correspondence Address:

Pretibial myxedema (PTM) is an infiltrative dermopathy seen in Graves' disease. It is also infrequently associated with hypothyroidism. Here, we describe a rare case of PTM with hypothyroidism in which thyroid-stimulating hormone receptor antibodies were found. An 82-year-old female presented with a 1-year history of a large pruritic plaque which was present over both her legs and feet. Histopathology of a skin biopsy showed markedly increased dermal mucin. These changes were suggestive of PTM. This case provides evidence that an autoimmune mechanism could play a central pathogenetic role in such cutaneous manifestations.


How to cite this article:
Oh SY, Cho HK, Jung YY, Lee MK. A case of pretibial myxedema associated with hypothyroidism and thyroid-stimulating hormone receptor antibodies.Dermatol Sin 2019;37:166-169


How to cite this URL:
Oh SY, Cho HK, Jung YY, Lee MK. A case of pretibial myxedema associated with hypothyroidism and thyroid-stimulating hormone receptor antibodies. Dermatol Sin [serial online] 2019 [cited 2022 Nov 30 ];37:166-169
Available from: https://www.dermsinica.org/article.asp?issn=1027-8117;year=2019;volume=37;issue=3;spage=166;epage=169;aulast=Oh;type=0