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   Table of Contents - Current issue
Coverpage
July-September 2021
Volume 39 | Issue 3
Page Nos. 115-166

Online since Monday, September 20, 2021

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EDITORIAL  

Recent advances in noninvasive imaging of the skin – dermoscopy and optical coherence tomography p. 115
Li-Wen Chiu, Stephen Chu-Sung Hu
DOI:10.4103/ds.ds_36_21  
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ORIGINAL ARTICLES Top

Facilitated delivery of topical steroids after fractional ablative carbon dioxide laser failed to prevent the postthyroidectomy hypertrophic scar p. 118
Ko-Chien Lin, Shao-Chun Wu, Shun-Yu Chi, Hui-Ping Lin, Cen-Hung Lin, Yueh-Ju Tsai, Mu-Han Hsieh, Shiun-Yuan Hsu, Ching-Hua Hsieh
DOI:10.4103/ds.ds_29_21  
Background: The ablative fractional laser can destroy the epidermal barrier and enhance the infiltration and distribution of drugs into the dermis. Objectives: This study was designed to investigate whether steroid delivery followed by the fractional ablative laser can prevent the formation of postthyroidectomy scar. Methods: This prospective split-scar design study recruited 12 adult female patients who underwent thyroidectomy between March 2018 and December 2018. The whole scar was treated with a fractional ablative carbon dioxide laser with topical 0.05% clobetasol propionate ointment only applied on the treatment side. The Patient and Observer Scar Assessment Scale (POSAS) questionnaire was used for outcome assessment at 1 year following the first treatment. The follow-up assessment by scar esthetic scale using digital photographs at 6 months and 1 year after first treatment was also done by three blinded plastic surgeons. Results: The POSAS revealed the improvement was not significant on vascularity, pigmentation, thickness, relief, pliability, surface area, and overall opinion on the improvement (all P > 0.05). The digital photographs evaluation also did not reveal a significant difference between the treatment side and control side. The overall esthetic score in the assessment of digital photographs was 4.4 ± 1.5, 4.2 ± 1.9, and 3.4 ± 1.9 at 6 months, and 2.8 ± 1.9, 3.1 ± 1.9, and 2.4 ± 2.1 at 1 year, with 0–10 indicating totally identical to significantly different comparing the whole scar with surrounding normal skin. Conclusion: This prospective scar-split study revealed that the application of topical steroid after fractional ablative carbon dioxide laser has no significant effect to prevent the formation of postthyroidectomy scar.
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The influence of gender and smoking on hidradenitis suppurativa: A retrospective study of 161 patients in Taiwan p. 125
Chia-Bao Chu, Wan-Lin Li, Sheng-Hsiang Lin, Chao-Kai Hsu, Chao-Chun Yang, Shaw-Jenq Tsai
DOI:10.4103/ds.ds_32_21  
Background: Hidradenitis suppurativa (HS) is a severe dermatological disease that significantly reduces life quality. However, the etiology of this disease remains largely unknown. Objectives: We sought to identify the factors associated with clinical presentation and the severity of HS. The features of HS between genders and smokers/nonsmokers were compared. Methods: A single-center retrospective study of 161 patients with HS was conducted and analyzed. Results: The male-to-female ratio in HS was approximately 2:1 in Taiwan. The severity of HS was significantly associated with smoking (odds ratio 2.20, P = 0.018). HS in men more frequently occurred in the gluteal region. Nonsmokers in HS tended to have earlier onset age and axillary lesions. Smokers were prone to have exclusive gluteal involvement and negative family history of HS. Conclusion: Our data revealed smoking correlated with the severity of HS. Smoking status and gender influence the clinical characteristics in HS.
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BRIEF REPORT Top

Eosinophilic pustular folliculitis associated with Demodex overgrowth or demodicosis on the face – A report of five cases p. 132
Hui-Peng Huang, Chao-Kai Hsu, Sheau-Chiou Chao, Chao-Chun Yang, Gwo-Shing Chen, Chih-Hung Lin, Chang-Ming Huang, Julia Yu-Yun Lee
DOI:10.4103/ds.ds_25_21  
Eosinophilic pustular folliculitis (EPF) is classified into Ofuji disease, immunosuppression-associated EPF, and infancy-associated EPF. The association of EPF with Demodex infestation is rarely reported. We report five cases of EPF with Demodex overgrowth. All patients were young females presenting with recurrent, itchy papulopustules on the face for 2 months to 2 years. Laboratory tests revealed eosinophilia (n = 2) and iron deficiency anemia (n = 1). Skin biopsy of papulopustular lesions was performed in each patient, and all revealed folliculocentric infiltration with eosinophils. Infundibular pustules containing Demodex mites were found in two patients. All patients had high Demodex densities examined by superficial needle-scraping method (7–18 mites/5 pustules) and/or thumbnail-squeezing method (37–255 mites/cm2). Based on the clinical and laboratory findings, the patients were either first treated as having demodicosis or as having EPF. According to the treatment responses, the cases might represent Demodex-induced EPF or EPF-like reaction (Cases 1–3) or demodicosis superimposed on EPF (Cases 4 and 5). In sum, we report five cases of EPF with Demodex overgrowth (demodicosis). These cases illustrate that the possibility of Demodex overgrowth should be considered in cases of EPF with incomplete treatment response to indomethacin and/or oral corticosteroids. Conversely, EPF should be considered in cases of demodicosis with incomplete responses to antiparasitic treatment.
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CORRESPONDENCES - INFECTIONS Top

Histoid leprosy complicated with Charcot neuroarthropathy: A case report p. 137
Jen-Hao Hsu, Yu-Hung Wu, Pa-Fan Hsiao
DOI:10.4103/ds.ds_26_21  
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Actinomycetoma caused by Nocardia brasiliensis successfully treated with antibiotics: A case report p. 139
Yi-Teng Hung, Ting-Shu Wu, Yu-Han Hsueh, Hsuan-Ning Wang, Pei-Lun Sun
DOI:10.4103/ds.ds_27_21  
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Recalcitrant giant genital wart treated with the combination of measles–mumps–rubella vaccine and human papillomavirus vaccine p. 141
Tzu-Yu Weng, Woan-Ruoh Lee, Donald Liu
DOI:10.4103/ds.ds_31_21  
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CORRESPONDENCES - TUMORS Top

Postirradiation multiple minute digitate porokeratosis: A case report p. 143
Xiao-Feng Yao, Yu-Hung Wu
DOI:10.4103/ds.ds_13_21  
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Juvenile folliculotropic mycosis fungoides mimicking tinea capitis: A case report and literature review p. 145
Lai-Ying Lu, Hsi Yen, Pei-Lun Sun, Yen-Lin Huang, Chun-Wei Lu
DOI:10.4103/ds.ds_15_21  
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Spontaneous regression of hidroacanthoma simplex after skin biopsy p. 147
Takahiro Koike, Hiraku Kokubu, Toshifumi Takahashi, Toshihiro Tanaka, Noriki Fujimoto
DOI:10.4103/ds.ds_19_21  
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Actinic granuloma successfully treated with low-dose doxycycline p. 149
Chun-Hsien Huang, Ching-Chi Chi, Wei-Ti Chen
DOI:10.4103/ds.ds_28_21  
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Squamous cell carcinoma arising in a verrucous cyst-like lesion: A case report p. 151
Chi-Hsuan Chen, Chao-Chun Yang, Yu-Yun Lee, Yin-Yu Ho
DOI:10.4103/ds.ds_30_21  
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CORRESPONDENCES - AUTOIMMUNITY Top

Statins did not reduce the mortality risk in patients with bullous pemphigoid: A population-based cohort study p. 153
Chen-Yi Wu, Chun-Ying Wu, Yi-Hsian Lin, Yun-Ting Chang
DOI:10.4103/ds.ds_14_21  
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Complete remission of scleredema adultorum of Buschke associated with multiple myeloma after bortezomib-based treatment and autologous peripheral blood stem cell transplantation p. 155
Hsing-Jou Su, Yao-Yu Chang, Chau Yee Ng
DOI:10.4103/ds.ds_16_21  
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Development of cutaneous hyperpigmentation and vitiligo during the recovery period of palmoplantar pustulosis in a patient of synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome: A case report p. 157
Mingwei Ma, Yanying Yu, Yihan Cao, Chen Li
DOI:10.4103/ds.ds_22_21  
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Radiation-induced bullous pemphigoid in a patient with Kaposi's sarcoma p. 159
Jia-Di Lin, Sung-Jen Hung
DOI:10.4103/ds.ds_23_21  
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Pediatric generalized lichen nitidus successfully treated with narrow-band ultraviolet B phototherapy: A case report p. 161
Ya-Tang Yang, Yu Yu
DOI:10.4103/ds.ds_33_21  
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CORRESPONDENCE - HEREDITARY Top

Treatment with sirolimus gel for folliculocystic and collagen hamartoma in tuberous sclerosis complex p. 163
Yuko Ehara, Yuichi Yoshida, Hiromi Higaki-Mori, Osamu Yamamoto
DOI:10.4103/ds.ds_20_21  
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CORRESPONDENCE - MISCELLANEOUS Top

Yellow vesicular palmar eruption in a young man with hyperbilirubinemia: Eccrine chromhidrosis p. 165
Ya-Hui Hsieh
DOI:10.4103/ds.ds_21_21  
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