| CASE REPORT |
|
| Year : 2020 | Volume
: 38
| Issue : 4 | Page : 236-239 |
|
|
Stevens–Johnson syndrome and toxic epidermal necrolysis related to immune checkpoint inhibitors: Two cases and literature review
Ting-Jung Hsu, Kwei-Lan Liu
Department of Dermatology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan
Correspondence Address:
Dr. Kwei-Lan Liu
No. 123, Dapi Rd., Niaosong District, Kaohsiung 83301
Taiwan
 Source of Support: None, Conflict of Interest: None  | 6 |
DOI: 10.4103/ds.ds_24_20
|
|
|
Immune checkpoint inhibitor-related Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) were rarely reported. We summarized the courses and the characteristics of two cases. The first case was a 74-year-old woman receiving pembrolizumab for Stage 2 urothelial cell carcinoma of the bladder. SJS developed 27 days after the first dose of pembrolizumab. The other case was a 67-year-old woman receiving atezolizumab for Stage 4 renal urothelial cell carcinoma. TEN developed after the eighth cycle of atezolizumab. Both patients were treated with low-dose corticosteroid and supportive management. Their wounds healed without dermatologic sequelae.
|
|
|
|
| [FULL TEXT] [PDF]* |
|
 |
|
