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Year : 2019  |  Volume : 37  |  Issue : 4  |  Page : 229-232

Cutaneous Mycobacterium haemophilum infection with jarisch–herxheimer reaction: A case report from Taiwan

1 Department of Dermatology, Chang Gung Memorial Hospital, Linkou, Taipei, Taiwan
2 Department of Dermatology, Chang Gung Memorial Hospital, Linkou, Taipei; Department of Medicine, College of Medicine; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Kwei-Shan, Taoyuan, Taiwan
3 Department of Internal Medicine, Division of Infectious Diseases, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
4 Department of Dermatology, Research Center of Cutaneous Disorders, Chung Shan Hospital, Taipei, Taiwan

Correspondence Address:
Dr. Hong-Shang Hong
No. 199, Dunhua N. Road., Songshan District, Taipei City 105
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ds.ds_7_19

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Mycobacterium haemophilum is a slow-growing and iron-dependent nontuberculous mycobacterium that can cause cutaneous ulcerations or nodular lesions. The diagnosis of cutaneous M. haemophilum infection is currently extremely rare in Taiwan. An 80-year-old Chinese man taking oral prednisolone for months presented with multiple erythematous as well as indurated and painful nodules over his right forearm. The diagnosis of M. haemophilum infection was confirmed through positive acid-fast staining – a technique used in histopathology and species identification – which was performed using molecular methods. Notably, Jarisch–Herxheimer reaction developed promptly during the antimicrobial therapy. Ideal skin culture conditions and specific molecular identification techniques are required for optimal detection of M. haemophilum.

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